Time-interval to adjuvant chemotherapy and postoperative management after upper abdominal surgical procedures in advanced ovarian cancer

IntroductionIn advanced epithelial ovarian cancer (EOC), longer time-interval from surgery to initiation of adjuvant chemotherapy (TITC) is associated with decreased survival. Adding upper abdominal surgical procedures (UAP) increases rates both complete gross resection and postoperative complications in EOC. Our objective was investigate the association UAP TITC. Moreover, if specific monitoring after most prevalent early detection management complications.Material methodsWomen diagnosed EOC 2014–2016 Stockholm/Gotland Region Sweden were identified Swedish Quality Registry for Gynaecologic Cancer. The between TITC investigated by multivariable linear regression adjusted predefined confounders. follow-up diaphragm resection, splenectomy cholecystectomy examined.Results240 women selected analysis. subjected similar a median 30 days (p = 0.99). despite higher rate major < 0.001) hospital stay 0.001), analysis there no prolonged TITC, mean difference ?2.27 (95% Confidence Interval (CI), ?5.99 ?1.45, p 0.23). After (diaphragm cholecystectomy), eventual interventions based on routine clinical rather than procedure-specific surveillance.ConclusionUAP does not prolong an increased length stay. Clinical non-specific surveillance sufficient detect UAP.